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[N-Methyl11 C](R)-1-(2-chlorophenyl)-N-(1-methylpropyl)-3-isoquinoline carboxamide [ 11 C]PK11195 is a widely used radiopharmaceutical for in vivo assessment of translocator protein 18 kDa (TSPO) activity using positron emission tomography. Here we present an interesting case of unusual distribution of [ 11 C]PK11195, that is a lack of uptake in tissues known for high expression of the TSPO.

Human Subject with Unexpected Biodistribution of [11C]PK11195