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With the increasing use of gonadotropin releasing hormone antagonist protocols, it has become an option to trigger ovulation with gonadotropin releasing hormone agonist which has several advantages over human chorionic gonadotropin triggering; among those an elimination or reduction in ovarian hyperstimulation syndrome, and a reduction in luteal phase discomfort. Thus, this paper questions the automated use of human chorionic gonadotropin for triggering of ovulation in assisted reproductive technologies.

HCG: Is it the Best Choice for Ovulation Triggering?