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Chronic hepatitis C virus (HCV) infection is estimated to affect approximately 3% of the world's population and, as such, is the most common blood-borne viral infection. Approximately 170-200 million people are considered to be infected worldwide, and in the United States as many as 5 million may have chronic HCV [1 3]. As is well known, people with HCV are often asymptomatic for a decade or more after they are initially infected and thus the risk of liver fibrosis, cirrhosis, hepatocellular cancer and mortality is increased if HCV is not promptly diagnosed and treated.

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Hepatitis C and Psychiatric and Substance Use Disorders Co-morbidities; Caring for People with Hepatitis C: Lessons from the Past that Inform Expectations in the Future