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In 2009, the European Vasculitis Study Group reported the results of CYCLOPS, a randomized controlled trial, in which pulse cyclophosphamide (CYC) was found to be similar to a daily CYC regimen in inducing remission in patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV). We herein conducted an observational study to describe our experience with Japanese AAV patients treated with pulse CYC according to the CYCLOPS protocol.

internal medicine

Experience with Seven Japanese Patients with Antineutrophil Cytoplasmic Antibody-associated Vasculitis Treated with Remission-induction Therapy with Intravenous Cyclophosphamide according to the CYCLOPS Protocol