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A treatment strategy to inhibit nonsteroidal anti-inflammatory drug (NSAID)-induced small intestinal lesions has not yet been established. To clarify whether monotherapy with a gastromucoprotective drug, geranylgeranylacetone (GGA), inhibits NSAID-induced acute mucosal injury of the upper digestive tract and small intestine.

internal medicine

Geranylgeranylacetone, a Gastromucoprotective Drug, Protects Against NSAID-induced Esophageal, Gastroduodenal and Small Intestinal Mucosal Injury in Healthy Subjects: A Prospective Randomized Study Involving a Comparison with Famotidine