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Adverse skin reactions as a local side effect of nicotine patches sometimes interfere with smoking cessation therapy. We studied the effects of semipermeable membrane dressings (SMD) used under nicotine patches (NP) on nicotine absorption, as assessed according to the urinary cotinine levels, and skin symptoms.

Semipermeable Membrane Dressings Can be Used with the Nicotine Transdermal System and Do Not Interfere with Nicotine Absorption