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An 86-year-old woman was admitted to our hospital because of a deep coma. Although she had suffered from chronic bronchitis and congestive heart failure, the symptoms and signs were stable and she was in her usual state of health until the morning of the day of admission. On the evening of admission day, her husband found her unconscious when he returned home from shopping. A volume of vomit that included numerous white pills was found around her. She had been prescribed 3 mg of benzodiazepine medicine, Etizolam, as a daily dose by her primary physician, and the pills in the vomit appeared to be this drug. On admission, she was in a deep coma. Her extremities showed no movement on noxious stimuli, but her brainstem reflexes such as light reflex were intact. Blood chemistry

internal medicine

Recovery of Cerebral Blood Perfusion from Transient Hypo-Perfusion Due to Acute Benzodiazepine Poisoning Coinciding with Generalized Convulsion as Withdrawal Syndrome