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A 59-year-old Japanese woman was diagnosed in 1998 with systemic sclerosis (SSc). The patient presented with a one-month history of postprandial vomiting prior to hospitalization. The patient underwent esophago-gastroduodenoscopy which revealed a diaphragm-like stricture in the second part of the duodenum in January 2004. Unexpectedly, the patient had not used NSAIDs for any long period of time. Retrospective endoscopic findings from 2000 showed the presence of duodenal circular erosions at the same site. This is the first report of a patient diagnosed with SSc who also presented with endoscopic evidence of a stricture of the duodenum, unrelated to NSAIDs.

Diaphragm-like Stricture in the Duodenum in a Patient with Systemic Sclerosis: Unrelated to Non-steroidal Anti-inflammatory Drug Use