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An indocyanine green derivative (ICG-sulfo-OSu) was used as the labeling substance for monoclonal antibody, and a fluorescence imaging system appropriate for ICG-sulfo-OSu excitable by infrared rays (IR) was developed. The goal of this study was to demonstrate antibody labeling at the tissue level using this new imaging system.

Labeled Carcinoembryonic Antigen Antibodies Excitable by Infrared Rays. A Novel Diagnostic Method for Micro Cancers in the Digestive Tract.