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The objective of the study was to determine the correlations between cognitive impairment in HIVinfected patients with early syphilis and mental disorders. 65 HIV-infected patients with early syphilis were examined by a clinical method and BNCE test. We revealed a high incidence of addictions (46.2 %). Cognitive impairment was found in 43.1 % of patients and was characterized by mild cognitive disorders. The severity of cognitive impairment was linked to hepatitis C co-infection (R = –0.38, p = 0.003), substance abuse (R = –0.39, p = 0.002) and intravenous drug use (R = –0.51, p < 0.0001). Cognitive impairment was associated with mental disorders due to brain damage (R = –0.93; p < 0.0001), dependence on stimulants (R = –0.69; p = 0.014), opiate dependence (R = –0.48; p < 0.001), and dependence on alcohol (R = –0.28; p = 0.037). Refs 15. Tables 2.

Cognitive impairment and mental disorders in HIV-infected patients with early stages of syphilis