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Undifferentiated embryonal sarcoma, an infrequent malignant mesenchymal liver tumor, occupies the third place in frequency of primary neoplasms of the liver in infancy. It has a fast-growing rate; the most frequent symptoms are pain and abdominal mass, also jaundice, weight loss, fever, emesis and hepatomegaly. The diagnosis is made taking into account the imaging findings, immune-histochemical studies and pathological analysis, the latter providing the definitive diagnosis. The prognosis of this tumor was initially poor, with survival rates of less than 1 year; however, with the introduction of chemotherapy associated with surgical resection, long-term survival has improved with the possibility of cure, directly related to timely treatment. In this article, two cases of undifferentiated embryonal sarcoma in pediatric patients are presented, diagnosed in the Fundación Cardioinfantil–Instituto de Cardiología, confirmed by pathology. Finally, the histopathological characteristics, imaging findings, differential diagnoses and the therapeutic options used are discussed, as reported in the literature. Quintero-Rodríguez K, Villegas-González V, Pérez-Hidalgo JM, Pérez-Alvarado MC, Forero-Melo J. Septiembre Diciembre 2018 Pág 302 MEDICINA El sarcoma embrionario indiferenciado es un tumor hepático mesenquimal maligno poco frecuente, que ocupa el tercer lugar de las neoplasias primarias del hígado en la infancia, con mayor incidencia entre los 6 y10 años y predominancia en el sexo masculino. 2. Jefe del Departamento de Radiología e Imágenes Diagnósticas, Imagen Corporal y Radiología intervencionista, Fundación Cardioinfantil–Instituto de Cardiología. Bogotá, Colombia. 3. Radiólogos Departamento de Radiología e Imágenes Diagnósticas, Sección de Imagen Corporal, Fundación Cardioinfantil–Instituto de Cardiología. Bogotá, Colombia.

Sarcoma embrionario indiferenciado en dos pacientes pediátricos