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A conventional, precise, clear colorimetric technique that is additionally sensitive is evaluated for the appreciation of sulfadiazine medicine as a sharp form, as well as for different sorts of pharmaceutical with different doses.The technique is depended with the conjugation of Sulfadiazine (SUZ) antibiotic as well as the 3,5Di hydroxy benzoic acid (3,5DHB) agent with using the azo coupling reaction. The (3,5DHB) in the basic media to finally produce a ligand that interacts with Cobalt (II) to generate the strength orange complex color at room temperature.The result dye is having solubility in water as well as flexible additionally predestined colorimetrically with ultimate absorption at (436 nm).The calibration graph between the absorbance and the concentration appears that the concentration range from medicine was established with utilizing the Beer’s law was between (0.12 - 18 μg/ml). The eclecticism of the best empirical envelopes is tested. The accuracy additionally the precision for the procedure are calculated by the average recovery amounts (100.122%) as well as the main relative standard deviation amounts (0.762 %) appropriately .That the technique is established on the concentration .The Sensitiveness for the procedure is getten with molar absorptivity (2.24×104 l. .cm-1.mol-1). the Sandell sensitivity is tested ( 0.01 μg.cm-2). The analysis facts for The technique.It is agreed by the offical procedure. The common medicinal additive intervention has been checked. The established technique is analyzed successfully in assessing (SUZ) in various types of pharmaceutical.

ISM Analysis, Evolution, Human-type and Validation of UV–Spectrophotometric Techniques for Assessment of Sulfadiazine in Bulk and Cream Dose Forms