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Burkitt’s Lymphoma of the head and neck region commonly involves the facial bones in its endemic variant and Waldeyer’s ring in the sporadic variant. Base of skull is a rare site for primary Burkitt’s lymphoma, with nasal and neuro-ophthalmology symptoms as its presentation. We report a case of a three year-old girl presented with sudden and progressive bilateral eye blindness associated with bilateral inward squint, proptosis and nasal blockage. Imaging study demonstrated a large anterior skull base lesion with extension into ethmoid and sphenoid sinuses. Tumor was removed via open surgery and histopathological examination confirmed the diagnosis of Burrkitt’s lymphoma. Patient had permanent bilateral blindness postoperatively and succumbed two months after the initial presentation due to the agressiveness of the tumor. The late presentation, aggressiveness of the disease and lack of financial support contribute to her untimely demise. Burkitt’s Lymphoma of the base of skull warrants early tissue diagnosis by means of surgical intervention to ensure prompt commencement of treatment.

The Fast and Furious, a Rare Case of Primary Burkitt’s Lymphoma of the Skull Base