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Dipterous insects cause serious public health problems for both humans and animals (Linthicum, 2012). In Egypt, Culex pipiens (Diptera: Culicidae), has been investigated and declared as a vector of several diseases (El-Zayyat et al., 2017). It transmits Rift valley fever virus (Dodson et al., 2017), Japanese encephalitis (Chancey et al., 2015), Wuchereria bancrofti accredited for human lymphatic filariasis transmission (Joseph et al., 2011), and West Nile virus (Bassal et al., 2017). Culex pipiens was incriminated as the filarial vector in Egypt (El-Naggar et al., 2017) and has been recorded by all governorates without exception (Abdel-Shafi et al., 2016). Traditional insecticides were used to control mosquitoes (Killeen et al., 2017) but introduced problems in the environment by leaving undesirable residues in food, toxicological implications to human health, increased cost and handling hazards (Bonner and Alvanja, 2017). Flies have developed a certain level of resistance to most available insecticides ARTICLE INFO ABSTRACT Article History: Received: March 5, 2021 Accepted: March 28, 2021 Online: March 31, 2021

egyptian journal of aquatic biology and fisheries

Larvicidal, biological, and histopathological alterations induced by pomegranate peel extract, Punica granatum against Culex pipiens L. (Diptera: Culicidae)