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Background: In terms of pregnancy termination, an accurate and precise assessment of fetal lung maturity is considered as the most importance factor for determining the ideal time. A non-invasive way to do so is amniocentesis, however it is invasive way which can lead to little but real hazard to the pregnancy. So, noninvasive sonographic procedures to assess lung development is most required. Aim of the study: To study the role of fetal main pulmonary artery Doppler (MPA) indices in expectation of Fetal Lung Maturity (FLM) and determine a highly sensitive and specific cut point of Doppler indices. Patients and Methods: Our prospective cohort study included 200 pregnant women 38 weeks fulfilling the inclusion and exclusion criteria, A number 0f distinctive parameters where measured from the fetal pulmonary artery flow (FPAF) waveform (At/Et, S/D, PSV, PI and RI) for determination of neonatal Respiratory Distress Disorder (RDS) and compare the findings found in Doppler with clinical the resultant outcome. Results: About 46 (23%) fetuses who were RDS (+ve) and 154 (77%) fetuses without RDS (-ve). There was a positive correlation between At/Et and PSV, and an inversely correlation between PI and RI with RDS. There was no significant change in the S/D ratio. Strongest correlation was found with At/Et. AT/ET was significantly lower in the RDS +ve group and the development of neonatal RDS was anticipated with a cutoff point of 0.32, with a high sensitivity specificity, and accuracy (98.0%, 92.0%, and 95.0%) respectively. Conclusion: By using MPA At/Et FLM and Ne0natal RDS can be anticipated with both high sensitivity and specificity.

Role of fetal main pulmonary artery doppler indices in prediction of fetal lung maturity