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Patients and Methods: A cross sectional study was carried out on 60 adult patients with advanced liver cirrhosis (Child’s C) who showed a low ejection fraction (EF) of <55 on ECHO. CCM related parameters including ejection fraction, left atrial and left end systolic/diastolic ventricular diameters (LAD, LVEDD) were measured using ECHO. All patients were assessed for AI by measuring fasting serum cortisol level using (Automated Chemoiluminescence Cobas e411 analyzer and EIA1887 kit). CCM related selected parameters were compared between those with and without AI. Results: The mean age was 63.83±7.64 with male sex predominance (87.4%). Their mean EF was 39.17±7.34, while 88.4% of them had a high LVEDD with a mean of 62.31±10.21 mm. The mean morning fasting free serum cortisol level was 7.95±5.23 mcg/dl with 48.4% of them having AI. Comparison of those with and without AI showed that the former group had a higher LAD (43.26±10.04 vs 42.76±7.64), LVESD (50.83±10.66 vs. 48.08±8 .17) and LVEDD (64.83±9.95vs. 59.94±9.97)) respectively. However, the difference was not statistically significant (P>0.05). There was no significant correlation between any of the CCM parameters or those of hepatic decompensation and the fasting serum cortisol level among the studied group (P>0.05).

Evaluation of Cirrhotic Cardiomyopathy related Parameters in Child’s C Patients With and without Adrenal Insufficiency