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Coordenacaode Aperfeicoamento de Pessoal de Nivel Superior, Brasil(CAPES), Finance Code 001. The authors thank theBrazilian funding agencies CNPq, FAPESB and FAPESP(PROEM 2014/50299-5, research grant 2013/01710-1 andTable 2. Inhibition percentage of the activity of the AChE-ICERSampleAChE-ICERinhibitionactivity / %SampleAChE-ICERinhibitionactivity / %LA01IS 6.70 ± 0.8 LA01HS 32.7 ± 3.3LA02IS 14.6 ± 2.4 LA02HS 27.4 ± 0.7LA24IS 18.0 ± 1.3 LA24HS 30.3 ± 4.1LA32IS 13.4 ± 0.9 LA32HS 6.70 ± 0.5LA39IS 17.1 ± 1.7 LA39HS 18.5 ± 4.0LA54IS 16.1 ± 1.1 LA54HS 24.5 ± 0.7LA01IW 10.3 ± 4.7 LA01HW 28.4 ± 0.2LA02IW 7.60 ± 3.8 LA02HW 27.2 ± 0.3LA24IW 15.0 ± 1.1 LA24HW 24.4 ± 3.2LA32IW 11.5 ± 1.1 LA32HW 22.2 ± 0.8LA39IW 23.3 ± 1.6 LA39HW 23.2 ± 1.6LA54IW 14.4 ± 0.1 LA54HW 29.3 ± 4.5Galanthaminea 87.4 ± 2.2aPositive control of acetylcholinesterase (AchE; 100 μM). AChE-ICER:AChE immobilized enzyme reactor; LA01-LA54: leaf samples ofL. alba accessions; IS: infusion summer; HS: hydroalcoholic summer;IW: infusion winter; HW: hydroalcoholic winter. PD grant 2014/11640-3) for their financial support andscholarships. A. F. B., E. R. P. F., D. P. B., C. L. C. andP. C. L. N. are grateful to CNPq for research fellowships.

journal of the brazilian chemical society

Application of LC-DAD Metabolic Fingerprinting in Combination with PCA for Evaluation of Seasonality and Extraction Method on the Chemical Composition of Accessions from Lippia alba (Mill) N. E. Brown and Biological Activities