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Surgical correction is the fundamental strategy for severe rheumatic mitral regurgitation as (MR) as medical management for MR can not prevent the hemodynamic consequences of severe MR in the asymptomatic and minimally symptomatic subjects. The purpose of this study is to assess the impact of duration of progressive rheumatic MR on LVEF, PH, LV and right ventricular dysfunction and decide about the selection of optimal timing for surgical intervention in our patient population. Material and methods: This study involves the data of 30 patients of MVR divided over 2 groups, from 1st January 2015 to 31st December, 2018 and follow up of the survivors. There were (a) 12 cases of isolated severe MR described as MR and (b) 18 cases of severe MR associated with mild MS described as MS +MR. Changes in echocardiographic parameters in both the groups after MVR, LVEF, LVESD, LV end diastolic diameter (LVEDD), PASP and NYHA functional class were assessed, analyzed and compared at 30 and 180 days. Results: In the postoperative period after 30 days, improvement of NYHA status were observed to be higher in 13 survivors with MS +MR from III to I while it was 6 in MR group. This improvement noted more in younger group below 40 years. NYHA changes from III to II was observed in 4 in each in both groups more in older group above 40 years. At 180 days, 1 each from NYHA II improved to I in younger group. Out of the 2 post operative mortality, there was 1 in MR group who had post operative RV dysfunction and died after discharge on 29th day and 1 in MS+MR group and who died of respiratory failure after 7 days though the cardiac indices improved and both were in older group. Conclusion: MVR can reversely remodel hearts and restore LV function with relatively preserved LV

international journal of contemporary medical research

​A Comparative Study of Changes in Left Ventricular Function after Mitral Valve Replacement in Patients with Severe Rheumatic Mitral Regurgitation with and without Mild Mitral Stenosis

​A Comparative Study of Changes in Left Ventricular Function after Mitral Valve Replacement in Patients with Severe Rheumatic Mitral Regurgitation with and without Mild Mitral Stenosis

A Comparative Study of Changes in Left Ventricular Function after Mitral Valve Replacement in Patients with Severe Rheumatic Mitral Regurgitation with and without Mild Mitral Stenosis