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The MetS (metabolic syndrome) is one of the main risk factors for cardiovascular disease and obesity is one of the major markers of its progression. The aim of this study was to know the comparative differences of waist circumference while predicting the relevant optimal cut-off in Turkman and non-Turkman people in the north of Iran. In our study 248 subjects aged 25-70 years have been chosen from 25 clusters with 10 cases. ATP-III method was used for diagnosis of MetS. The optimal cut-off and the corresponding sensitivity and specif icity for age have estimated in the threshold that maximizes the sum of sensitivity and specif icity or equivalently maximizes in ROC (receiver operating characteristic) curve operating points. The statistical differences were signif icant between Turkman and non-Turkman groups in almost all the parameters such as HDLc, LDLc, cholesterol, TG, and FBS. In non-Turkman group, the association between WC and TG, LDLc and FBS showed a positive relationship but it was negative with HDLc. The association between WC and cholesterol level was not signif icant. The cut-off values of WC for hyper TG, HDLc low and diabetes was respectively higher 6.0, 7.25 and 8.25 cm in non-Turkman group than in Turkman group, however; based on hypercholesterolemia and LDLc it was lower in non-Turkman than in Turkman group. The differences in the above parameters while comparing separately between male and females is also found interesting. Conclusively, the gene has a protective role based on thecholesterol inTurkmanpeople. Abstract

Cut-off Point of Waist-circumference for Metabolic Syndrome Components among Turkman and Non-Turkman Ethnic Adults in the North of Iran