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The advent of novel molecular targets has dramatically changed the treatment landscape of lung cancer in recent years. Isochorismatase domain-containing protein 1 ( ISOC1 ) has been reported as a potential biomarker in gastrointestinal cancer, while its function in lung cancer has not been determined.

translational lung cancer research

Isochorismatase domain-containing protein 1 (ISOC1) participates in DNA damage repair and inflammation-related pathways to promote lung cancer development