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Despite advances in systemic therapy and improvements in survival for advanced epidermal growth factor receptor ( EGFR ) mutant non-small cell lung cancer (NSCLC), brain metastasis (BM) remains a poor outcome. Previous studies on risk factors for BM occurrence included unselected patients and biomarker prediction of BM in these populations were not well studied. We aimed to identify the role of epithelial mesenchymal transition (EMT) marker and clinical factors predicting BM in.

Vimentin expression status is a potential biomarker for brain metastasis development in EGFR-mutant NSCLC patients