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Precision Medicine Center of Oncology, the Affiliated Hospital of Qingdao University, Qingdao, China; Cancer Institute, Qingdao University, Qingdao, China; Department of Pathology, the Municipal Hospital of Qingdao, Qingdao, China; Department of Pathology, the Affiliated Hospital of Qingdao University, Qingdao, China; Department of Clinical Laboratory, BGI-Shenzhen, Shenzhen, China; Department of Pathology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China; BGI-Qingdao Institute, Qingdao SINO-GERMAN Ecopark, Qingdao, China Contributions: (I) Conception and design: H Hou, X Zhang; (II) Administrative support: H Hou, X Zhang; (III) Provision of study material or patients: D Jia, W Yan, C Wang, H Chen, W Huang, Y Li; (IV) Collection and/or assembly of data: H Hou; (V) Data analysis and interpretation: H Hou, X Zhang, Z Li; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Correspondence to: Xiaochun Zhang. Precision Medicine Center of Oncology, the Affiliated Hospital of Qingdao University, Qingdao University, 16 Jiangsu Road, Qingdao 266005, China. Email: zxc9670@qdu.edu.cn.

translational cancer research

KIT/PDGFRA/KDR amplification defines a novel molecular subtype of adenoid cystic carcinoma patients who may benefit from treatment with tyrosine kinase inhibitors