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China School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, China; Department of Clinical Laboratory, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China Contributions: (I) Conception and design: Q Feng, N Zhang; (II) Administrative support: Q Feng; (III) Provision of study materials or patients: N Zhang, Q Yang, X Guo; (IV) Collection and assembly of data:N Zhang, Q Yang, X Guo , Y Xue, C Duan, H Wang; (V) Data analysis and interpretation: N Zhang, X Guo, Q Yang; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Correspondence to: Quanling Feng. Department of Clinical Laboratory, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450001, China. Email: zzufql@126.com; Nan Zhang. School of Pharmaceutical Sciences, Zhengzhou University, 100 Kexue Avenue, Zhengzhou 450001, China. Email: zhangnan@zzu.edu.cn.

translational cancer research

Involvement of DNA methyltransferase 1 (DNMT1) and multidrug resistance-associated proteins in 2-methoxyestradiol-induced cytotoxicity in EC109/Taxol cells