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School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, China; Key Laboratory of Fertility Preservation and Maintenance (Ningxia Medical University), Ministry of Education, Yinchuan, China; Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai, China; Department of Oncology, General Hospital of the Ningxia Medical University, Yinchuan, China Contributions: (I) Conception and design: BX Liu, T Li; (II) Administrative support: J Chen; (III) Provision of study materials or patients: Q Shen, J Chen, HY Jiao; (IV) Collection and assembly of data: J Chen, BX Liu, Q Shen; (V) Data analysis and interpretation: BX Liu, Q Shen, J Ling, M Xiao; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. These authors contributed equally to this work. Correspondence to: Prof. Tao Li; Prof. Haiyan Jiao. Department of Oncology, General Hospital of the Ningxia Medical University, 1160 Shengli Road, Yinchuan 750004, China. Email: lit1979@163.com.

Limonin inhibits angiogenesis and metastasis of human breast cancer cells by suppressing the VEGFR2/IGFR1-mediated STAT3 signaling pathway