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Department of Breast Surgery, the First Affiliated Hospital of China Medical University, Shenyang, China; Department of Surgical Oncology and General Surgery, Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, Ministry of Education, The First Affiliated Hospital of China Medical University, Shenyang, China Contributions: (I) Conception and design: H Dong, L Yao, Y Xu; (II) Administrative support: Y Xu; (III) Provision of study materials or patients: H Dong, L Yao; (IV) Collection and assembly of data: M Wang, M Wang, X Li, X Li; (V) Data analysis and interpretation: X Sun, X Yu, J Guo; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. These authors contributed equally to this work. Correspondence to: Professor Yingying Xu. Department of Breast Surgery, the First Affiliated Hospital of China Medical University, 155 North Nanjing Street, Shenyang 110001, China. Email: xuyingying@cmu.edu.cn.

Can ACEI/ARB prevent the cardiotoxicity caused by chemotherapy in early-stage breast cancer?—a meta-analysis of randomized controlled trials