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Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Centre for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin, China; Department of Gynecologic Oncology, Tianjin Central Hospital of Gynecology Obstetrics, Affiliated Hospital of Nankai University, Tianjin, China Contributions: (I) Conception and design: J Zeng, M Meng; (II) Administrative support: P Wang, P Qu; (III) Provision of study materials or patients: J Chen, B Zhang; (IV) Collection and assembly of data: D Zhang; (V) Data analysis and interpretation: Q Pang; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. These authors contributed equally to this work. Correspondence to: Qingsong Pang. Tianjin Medical University Cancer Institute and Hospital Huanhuxi Road, Tianjin 300060, China. Email: pangqingsong2013@163.com.

translational cancer research

Assessing cumulative dose distributions in combined external beam radiotherapy and intracavitary brachytherapy for cervical cancer by treatment planning based on deformable image registration