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Department of Gastric Surgery, Fudan University Shanghai Cancer Center, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Pathology, Ruijin hospital affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China; Department of Gastrointestinal Surgery, Ruijin hospital affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China Contributions: (I) Conception and design: JP Gao, T Yu, ZL Zhu, Y Xuan; (II) Administrative support: ZL Zhu, Y Xuan; (III) Provision of study materials or patients: ZL Zhu, Y Xuan; (IV) Collection and assembly of data: JP Gao, ZL Zhu; (V) Data analysis and interpretation: JP Gao, T Yu, ZL Zhu, Y Xuan; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. These authors contributed equally to this work. Correspondence to: Yi Xuan. Department of Gastric Surgery, Fudan University Shanghai Cancer Center, 270 Dongan Road, Shanghai 200032, China; Department of Oncology, Shanghai Medical College, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China. Email: xuanyi0118@163.com; Zhenglun Zhu. Department of Gastrointestinal Surgery, Ruijin hospital affiliated to Shanghai Jiaotong University School of Medicine, 197 Ruijin 2nd Road, Shanghai 200025, China. Email: zzl11703@rjh.com.cn.

High expression of GNB4 predicts poor prognosis in patients with Helicobacter pylori-positive advanced gastric cancer