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Ranking as the fourth common cancer all around the world, gastric cancer (GC) remains the second cause for death among all the cancer-related death worldwide (1,2). Clinically, surgery with or without chemo or radio therapy is the most recommended curative approach. However, the poor prognosis, relatively short survival and rather low overall survival rate in advanced GC still raises the necessity for novel treatment methods with better therapeutic outcomes (2). It was well reported that the intratumor Original Article

MiR-185-3p regulates epithelial mesenchymal transition via PI3K/Akt signaling pathway by targeting cathepsin D in gastric cancer cells