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To determine the feasibility of secondary biopsy of metastatic castration-resistance prostate cancer based on the "4W1H-When, Who, Why, Where, How" principle and analyze the factors that affect tumor detection. Its application will further direct the patients for individualized precision therapy.

translational andrology and urology

Application of metastatic biopsy based on “When, Who, Why, Where, How (4W1H)” principle in diagnosis and treatment of metastatic castration-resistance prostate cancer