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In this study, one triterpenoid compound from  n - hexane fraction of  Lantana camara Linn leaves has cytotoxic activity was isolated. Isolation was carried out using  gravity chromatography column and purification by recrystallization method. Isolated compound was obtained white solid with melting point 252-253 o C. The structure of isolated compound was elucidated using spectroscopic analysis Ultraviolet (UV), Infrared (IR),  1 H-Nuclear Magnetic Resonance ( 1 H-NMR),  13 C-Nuclear Magnetic Resonance ( 13 C-NMR) Heteronuclear Multiple Bond Connectivity (HMBC),  Heteronuclear Multiple Quantum Correlation (HMQC), Distortionless Enhancement Polarization Transfer (DEPT) and comparative literature data, identified as Lantadene A ( 22 β -angeloyloxy-3-oxoolean-12-en-28-oic-acid ) with molecule formula C 35 H 52 O 5 . The Lantadene A compound was evaluated for cytotoxic activity against shrimp larvae  Artemia Salina Leach using  Brine Shrimp Lethality Test (BSLT) method, showed strong cytotoxic activity with an LC 50 value of 48.97 µg/mL.

A Cytotoxic Compound from n-Hexane Fraction of Lantana camara Linn Leaves