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The present study was designed to conduct with the main purpose of evaluation of antimicrobial activity of solvent extracts and essential oil of leaves of Cipadessa baccifera (Roth.) Miq. The plant samples for investigation were collected from Thavarekere and Savandurga, Magadi Taluk, Bengaluru Rural district, and outskirts of Bengaluru, and identification was authenticated by National Ayurveda and Dietetics Research Institute, Bangalore; vide voucher specimen number, RRCBI-8971.The dried leaf samples were pulverized in an electric blender and the powdered material was stored in air tight containers for further analyses. The leaf samples were subjected to sequential extraction using Soxhlet apparatus, and extracted exhaustively in organic solvents such as, hexane, chloroform, methanol and water. The essential oil from leaf sample was extracted in Clevenger apparatus. The sequential extracts and essential oil of leaf parts of C. baccifera (Roth) Miq. were subjected to evaluation of antimicrobial activity against diarrhoea, skin, wound and oral infections causing selected pathogens, including 07 Gram positive, 06 Gram negative bacteria and 06 fungal strains. Results revealed that essential oils and crude solvent extracts leaves of Cipadessa baccifera showed significant anti-bacterial potential against diarrhoea, skin wound and oral pathogens inhibiting both Gram positive, Gram negative and fungal species. The broad spectrum of anti-bacterial activity of C. baccifera revealed in the present investigation gives scientific validity for its usage in treatment of dysentery, skin related disorders and wounds in traditional and folk medicines.

Evaluation of Antimicrobial Activity of Solvent Extracts and Essential Oil of Leaves of Cipadessa baccifera (Roth.) Miq.