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Background:  Compliance for taking medication to become an important thing for a patient with hypertension. Compliance is needed to control blood pressure and prevent complication. The purpose of this study was to analyse the factors that influence patients adherence to taking medicine.   Method : The study design was observational analytic using a cross-sectional approach. Samples were 225 patients with hypertension class 2 and 3, in Malang district, Indonesia. The sampling technique was done by using a multistage random sampling technique. The research instrument was in the form of a questionnaire. Data analysis was performed using the Pearson test and linear regression.   Results:  The results showed that patients adherence in taking medicine was 32.9% for the low category, 51.1% in the medium category and 16% in the good category. Factors influencing the adherence were ages (p-value: 0.002), turning to religion (p-value: 0.011), gender (p-value: 0.016) and suppressing competition activities (p-value: 0.063).   Discussion:  Demographic characteristics and focused emotional mastery influence taking the medication in patients with grade 2 and grade 3 hypertension. Strengthening coping strategies with transporting to coping emotions becomes very important to discuss in patients with grade 2 and grade 3 hypertension, so that adherence to hypertension is needed will be able to control blood pressure and prevent complications.

Determinants of Drug Adherence on Grade Two and Three Patients with Hypertension