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The accumulation of fundamental knowledge in the field of Hematology, Immunohematology, Pathophysiology, Biochemistry, Biophysics, Histology and other related medical specialties objectively contributed to the formation of a new medical discipline – Clinical Transfusiology. Unfortunately, today among some anesthesiologists and resuscitators there is an erroneous and potentially dangerous point of view regarding the importance of this discipline. Inertia of traditional views on blood loss, and an archaism of fundamental knowledge in the field of Clinical Transfusiology negatively affect the quality of writing clinical protocols of blood transfusion. The presence of many incorrect scientific articles in various peer-reviewed surgical journals (including journals with a high citation rating) forms a false idea among doctors about the pathophysiological mechanisms of blood loss, an adequate assessment of severity of the clinical condition of the patient. Such publications deprive the understanding of the mechanisms of compensatory systems of the organism, which resist massive blood loss and protect the body from death. Intensive care physicians and anesthesiologists should be aware that from the point of view of pathophysiologically, to maintain the compensatory reactions of the organism, primarily, the therapy must be directed at the elimination an acute deficit in circulating blood volume (CBV), secondly, the correction of coagulation factors, and only in the last instance – to a possible increase in the number of the oxygen-carrier [2].The severity of the patient's condition in acute massive blood loss does not depend directly on the indicators hematocrit and hemoglobin. The severity of the patient's condition determines the individual ability of the organism to resist hypoxia, the effectiveness of compensatory systems [3]. Therefore, the development and improvement of personalized express-diagnostic systems of functional state of Abstract: The focus of the article is rather situated on current faults and recommendations for transfusion of red blood assessment, clinical evaluation of changes in hematocrit. The main task of therapy for acute massive blood loss is not urgent thoughtless transfusion of red blood cells for the fast recovery of the hemoglobin and hematocrit levels. The oxygen-carrying capacity of blood does not directly reflect the delivery of oxygen to tissues. The severity of the patient's condition depends of individual ability of the organism to resist hypoxia, mechanisms resulting in physiological compensation for the anemia caused by blood loss. The main tasks of therapy are timely maintaining appropriate and effective compensatory adaptive reactions of an organism, providing of the sanogenetic processes. Quickly and comfortable algorithm assessment changes in hematocrit was presented for used in practice. Objective analysis hematocrit and hemoglobin levels should be carried out only in combination with data on blood pressure, pulse rate, respiratory rate, urine output and shock index.

Hematocrit, As Part of an Integrated Condition Assessment System of the Body