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Hyperkalemia is a condition commonly encountered in medical and surgical patients and can induce life-threatening cardiac arrhythmias if left untreated. Kayexalate is a cation-exchange resin frequently used to treat this condition. Although rare, there is a known relationship between kayexalate administration and bowel necrosis and it is therefore important to consider this in a patient with abdominal pain who has been treated with oral kayexalate [1,2]. We present a case of a surgical oncology patient who developed spontaneous bowel perforation in the setting of kayexalate administration.

Hyperkalemia Management in the Oncology Patient: A Case of Sodium Polystyrene Sulfate Induced Bowel Perforation