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.. Objectives: To determine the effect of LASIK on tear film stability. Study Design: Cross sectional, prospective study. Setting: The study was conducted in D. G. Laser Vision and Diagnostic Center, D.G. Khan, South Punjab, Pakistan. Period: From March 2016 to September 2016. Materials and Methods: One hundred patients (two hundred eyes) were selected for this study. SPSS version 20 was used to analyze the data. Categorical variables presented as frequency and percentages and numerical variables presented as mean ± standard deviation. Results: It is observed that values of tear break up time, Schimer I and Schimer II were decreasing at one week and one month post LASIK as compare to one week pre LASIK values. Mean tear break up time at one week of pre LASIK was 14.72 ± 1.08 seconds (P=0.000), at one week post LASIK was 13.64 ± 1.507 seconds (P=0.000) and at one month post LASIK was 13.02 ± 1.695 seconds (P=0.000). Conclusion: Laser in situ keratomileusis (LASIK) significantly changes tear film stability and tear secretions for at least one month post operatively.

LASIK; EFFECT ON TEAR FILM STABILITY