English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The main purpose of this study was to detect an association of cytoplasmic signal transducers and activators of transcription-1 (STAT1) with milk production traits in 472 Holstein and 283 Jersey cattle breeds of Turkey. This gene, located on chromosome 2, was chosen due to its role on development of mammary gland. A polymorphism of selected 314 bp allele fragment was detected by the restriction fragment length polymorphism analysis of polymerase chain reaction-amplified fragments (PCR-RFLP) method and also confirmed by DNA sequencing. The association tests were conducted between STAT1 genotypes and some economically important dairy traits. The genotypes for C/T as a single nucleotide polymorphism (SNP) were identified at interval 60 cM to 63 cM. The effects of STAT1 gene on milk production traits were not significant in Holstein cows, although animals with CT genotypes showed fairly close to significant value for the corrected 305 d milk yield. However, Jersey cows with TT genotype were 2.07 kg higher for test-day milk yield (P < 0.05), 0.13 kg for fat yield (P < 0.01) and 0.07 kg for protein yield (P < 0.05) compared with animals having CC and CT genotypes. Definitely, the further research should be conducted to search this gene intensively with larger samples to identify polymorphism and any association between the economically important traits and genotypic class in Holstein cows. Finally, based on the findings, it was concluded that STAT1 gene might be used as a potential candidate gene to improve milk yield and milk fat and protein contents in dairy cows breeding programs.

The Detection of STAT1 Gene Influencing Milk Related Traits in Turkish Holstein and Jersey Cows