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This work aims to study the appropriate method for extract Betel leaf as crude extracts to prepare as a natural antioxidant in moisturizing hand cream. Betel leaf was treated by 7 methods and the optimized method was selected for preparation of Betel leaf extract. The fresh Betel leaf and dried Betel leaf were used in this study. Betel leaf extracts were analysed for total phenolic content and essential oil as eugenol content. Then Betel leaf extracts were used as the one component for moisturizing hand cream. The lipid oxidation was evaluated by measurement on malondialdehyde content. The results revealed that an extracts solution from dried Betel leaf contained total phenolic content and eugenol content more than fresh Betel leaf. The ethanol extraction method was the optimum method since this method showed the maximum total phenolic content and eugenol content in dried Betel leaf as 5.26 g/100 g and 138.95 mg/100 g, respectively. The moisturizing creams were formulated by using crude Betel leaf extracts as the one composition compare with base cream (no addition of Betel leaf extracts). The moisturizing cream samples were analysed for malondialdehyde. its showed that the cream that contained Betel leaf extract contained malondialdehyde content lower than in cream base. Thus, crude extracts from Betel leaf showed the efficacy to reduce lipid oxidation reaction in moisturizing hand cream.

Efficacy of Betel Leaf Extracts as Antioxidant in Moisturizing Cream