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Methods: Naïve HIV infected patients were equally randomized either to receive stavudine 30mg once-daily or zidovudine standard dose regimens. Viral load, hemoglobin (Hb), alanine amino transferase (ALT), Body Mass Index (BMI), opportunistic infections (OIs) at baseline and six months were determined. Changes at baseline and six months were compared within and between-groups. Our outcome was the proportion of patients who attained VLS< 400 copies/mL at six months.

Virological Response Following Anti-Retroviral Therapy Employing Once-A-Day 30 mg of Stavudine in HIV-Infected Patients: A 24- Week Randomized Controlled Study in Dar Es Salaam, Tanzania