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In an oral iron absorption test (OIAT), the rise in plasma iron concentration after oral ingestion of iron is a measure of intestinal iron absorption. We describe results of the OIAT using a new co-processed compound between Ferrous By sglicinate Chelate and Alginic Acid named FERALGINE® in capsules. Methods: The study included all patients with IDA who had an OIAT performed at the Department of Transfusion Medicine of San Camillo Forlanini Hospital in Rome, Italy from June 2016 to September 2016 using two capsules containing each one 30 mg of elemental iron from FERALGINE®. A venous blood sample was drawn before and then 120 minutes after the intake of 2 capsules (60 mg of elemental iron) of FERALGINE® (TECNOFER® PLUS). Results: The patient characteristics were similar in terms of age, hemoglobin, ferritin and plasma iron. The fasting baseline plasma iron concentration was median 11.21 mg/dl. The maximum plasma iron concentration increase from baseline after 120 minutes of oral intake of FERALGINE® was median 111.0 mg/dl (T Students Test p<0.00001). Conclusion: OIAT performed with FERALGINE® capsules results in a statistically significant increase of plasma iron concentration after 120 minutes (p<0.00001) showing an excellent and quick oral bioavailability of the new patent-pending compound FERALGINE® in IDA patients.

journal of blood disorders and medicine

Oral Iron Absorption Test (OIAT): A Forgotten Screening Test for Iron Absorption from the Gastrointestinal Tract. A Case Series of 14 Iron Deficiency Anemia (IDA) Patients Treated with FERALGINE®