English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Chronic occupational exposure to heavy metals particularly cadmium, lead and chromium may result in renal alterations affecting both tubuli and glomeruli. We therefore examined the association of blood cadmium (B-Cd), blood lead (B-Pb), and blood chromium (B-Cr) with Estimated Glomerular Filtration Rate (eGFR) among artisans and petrol hawkers in Jos, Nigeria. Blood samples were collected from workers who were all men (n=400), drawn from welders, battery repairers, petrol hawkers, tin miners and car painters with age ranging from 15-60 years with a mean value of (35.99 ± 10.59). The control group (n=200) was within the range of 28-49 years and a mean value of (37.10 ± 5.45) and the duration of exposure was limited to between 1-8 years. 10 mL of blood was also collected into plain tubes from each subject. Samples were allowed to stand for 15 minutes after which they were centrifuged at 3000 rpm for 20 minutes and the serum separated with the help of a sterile Pasteur’s Pippette into cryovial containers. Samples were later stored frozen at -20°C pending analysis. Serum levels of heavy metals were done using AAS. Random Urine samples (5 mL), collected in sterile universal containers and used for the determination of micro albumin by latex agglutination methods. Serum Urea/Creatinine was done using COBAS C111 Chemistry auto analyzer. Data were analyzed using Statistical Package for Social Sciences (SPSS) version 23 and student t-test was used to compare mean values between the control and study groups. Statistically high levels of Serum Cd, Pb and Cr were detected among welders, car painters and petrol hawkers in addition to the levels of Urea, Creatinine and Micro albumin, which were also statistically increased and significant (P<0.05) among battery repairers, petrol hawkers, car painters and welders with a corresponding eGFR <90 mL/min for Car painters 77(96.3%), followed by battery repairers 60(75.0%), iron welders, 60(75.0%) and petrol hawkers 57(71.3%) respectively. We conclude that artisans and petrol hawkers in jos are prone to kidney damage due to the presence of lead, cadmium, and chromium.

Derangement of Kidney Biomarkers Associated with Blood Cadmium, Lead and Chromium in Artisans and Petrol Hawkers in Jos, Nigeria