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Weaver et al.1 recently described equations for estimating the median urinary albumin-to-creatinine ratio (ACR) from the protein-to-creatinine ratio (PCR) on the basis of median regression models for log ACR in a Canadian population–based cohort. Patients with kidney transplants (KTx) were excluded. The method is proposed, for example, for answering scientific questions where ACR is required and only measured PCR is available.2 Because this method is also of interest to the transplant community, we aimed to investigate the suitability of the equations in patients with KTx and a living kidney donor (LD) cohort. Therefore, we retrospectively identified 16,990 sameday/same-person pairs of ACR and PCR measurements in patients after KTx at our transplant center in Münster, Germany and 5304 same-day/same-person pairs of ACR and PCR measurements in the LD cohort. To estimate the median ACR of same-day measurements of PCR, we applied the following equations published by Weaver et al.1 (for all equations, the natural logarithmwith base e is taken):

journal of the american society of nephrology

The Estimation Formula for the Urinary Albumin-Creatinine Ratio Based on the Protein-Creatinine Ratio Are Not Valid for a Kidney Transplant and a Living Donor Cohort