Open AccessTrastuzumab‐Related Cardiotoxicity in Early Breast Cancer: A Cohort Study
Author(s) -
Bonifazi Martina,
Franchi Matteo,
Rossi Marta,
Moja Lorenzo,
Zambelli Alberto,
Zambon Antonella,
Corrao Giovanni,
La Vecchia Carlo,
Zocchetti Carlo,
Negri Eva
Publication year - 2013
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1634/theoncologist.2013-0065
Subject(s) - medicine , trastuzumab , cardiotoxicity , discontinuation , breast cancer , oncology , incidence (geometry) , cumulative incidence , cohort , cohort study , cancer , chemotherapy , physics , optics
Learning ObjectivesEvaluate the frequency of trastuzumab‐related serious cardiac events in clinical practice. Assess the cumulative incidence of cardiac disorders at 1, 2, and 3 years after first administration, irrespective of drug discontinuation. Identify predictors for the onset of cardiotoxicity.