Open AccessProlonged Versus Standard Gemcitabine Infusion: Translation of Molecular Pharmacology to New Treatment Strategy
Author(s) -
Veltkamp Stephan A.,
Beijnen Jos H.,
Schellens Jan H.M.
Publication year - 2008
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1634/theoncologist.2007-0215
Subject(s) - gemcitabine , deoxycytidine kinase , pharmacology , medicine , deoxycytidine , nucleoside , nucleoside analogue , pharmacokinetics , antimetabolite , pancreatic cancer , nucleoside transporter , chemotherapy , oncology , cancer , chemistry , biochemistry , transporter , gene
Learning Objectives After completing this course, the reader will be able to: Describe the molecular pharmacology of nucleoside analogues. Explain transport, metabolism, and elimination in relation to the activity of gemcitabine. Describe the clinical pharmacology of gemcitabine in relation to its rate of administration.Access and take the CME test online and receive 1 AMA PRA Category 1 Credit ™ at CME.TheOncologist.com