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570 História, Ciências, Saúde – Manguinhos, Rio de Janeiro The publication of Medicine at the border is relevant from the perspective of how we as citizens manage our health and are managed by local, national, regional and supra-national institutions looking to preserve global safety and health. The volume collectively shows how the history of infectious disease is central to the political, legal, and commercial history of nationalism, colonialism, and internationalism. The chapters are thematically organised into three parts: (a) the connection between national history and the emergence of international health structures over the twentieth century; (b) the issue of territorial health regulation and the movement of people across national borders; and (c) contemporary global epidemiological surveillance networks that increasingly bypass the nation-state. In a well-argued introduction, the editor, Alison Bashford, enables readers to draw connections between medicine, international relations, and human rights. Borders of many kinds, like quarantine lines, migration screening, and the home isolation of suspected virus carriers, have geopolitical implications, such as preventing disease outbreaks within sovereign states. However, the aspiration to prevent disease has resulted in pre-emptive activity that has transcended the nation-state (e.g. the European intervention in the Ottoman Empire) to prevent the spread of cholera, as attested by Patrick Zlyberman’s article. Alexandra Minna Stern’s nuanced chapter explores the tight nexus between commerce, international relations, US colonialism and philanthropic public health spearheaded by the Rockefeller Foundation. Sanjoy Bhattacharya’s article, based on extensive archival research at the World Health Organisation (WHO) archives, assesses the many complexities involved in the implementation of the smallpox eradication programme in India as it unfolded at the different levels of Indian administration. In their chapter, Theodore Brown, Marcos Cueto and Elizabeth Fee provide historical insights into the emergence of the terminology of global health and the role of the WHO as an agent in the transition from international to global health. From international to global: the geopolitics of disease prevention De internacional a global: a geopolítica da prevenção de doenças