English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

PURPOSE: Training generally promotes health and inhibits diseases. However, in patients with atopic dermatitis (AD), training and sweating are significant aggravating factors. This study examined the effect of high-intensity resistance training (HIRT) on AD-like skin lesions in mice.METHODS: Eight-week-old female BALB/c mice were divided into four groups (control, HIRT, AD-only, and AD+HIRT). The mice in the HIRT group performed vertical ladder climbing for four weeks.RESULTS: After four weeks of HIRT, histopathological examination revealed reduced epidermis/dermis and dermal infiltration of inflammatory cells in the mice ear tissue. Additionally, HIRT suppressed serum immunoglobulin (Ig) levels and mRNA expression of pathogenic cytokines in the ear tissue; further, it reduced the size and weight of the draining lymph node (dLN) and non-dLN (ndLN), and the pathogenic cytokine-related mRNA expression of CD4+T cells from dLNs and ndLNs. We thus observed a negative correlation between HIRT and AD symptoms in mice.CONCLUSIONS:The results show that HIRT exerts positive effects in patients with AD.

High-Intensity Resistance Training Suppresses Exacerbation of Atopic Dermatitis in Mice