English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

A bis-demethoxy curcumin microemulsion was successfully prepared using the method of pseudo-ternary phase diagrams combined with an orthogonal test in a 3-phase system (O phase=active ingredient; S phase=surfactants; W phase=water). The best transparent region for preparing the bis-demethoxy curcumin microemulsion was formed when Termul-200 (an alkylphenol polyether block copolymer emulsifier) and sodium dodecyl benzene sulfonate (SDBS) (4 : 1 w/w) were used as surfactants (S phase), isopropanol (30% in S phase) as a co-surfactant, and a bis-demethoxy curcumin DMF solution (30%) as the active ingredient (O phase). According to the infinite dilution region of the best phase diagram, the best ratio among O, S and W phases for preparing the bis-demethoxy curcumin microemulsion was a weight ratio of 4.5 : 20 : 75.5. Stability tests showed that all the indicators of our prepared microemulsion met the storage stability criteria. Our results suggested that the combination of the pseudo-ternary phase diagram and orthogonal test analysis provided an effective approach for designing a microemulsion formulation.

Preparation of a bis-demethoxy curcumin microemulsion based on pseudo-ternary phase diagrams and an orthogonal test analysis