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Background: Early recognition of mild cognitive impairment (MCI) and subtle changes to cognitive abilities that precede an MCI diagnosis has the potential to improve the efficacy of therapeutic treatment programs. Objective: The work addresses mobile games’ potential as empirical assessment tools for cognitive processes within the domains of attention, recognition, recall, and memory applied to game strategy. Methods: Two games have been developed with this objective. WarCAT is based on a familiar card game, War, and “Lock Picking” is a search for an optimal score, akin to finding the combination that opens a lock. Both games provide players with immediate feedback but engage different algorithms and heuristics to solve the respective problems at hand. Conclusions: By collecting player data on large scales to allow for baseline establishment of cognitive abilities across demographic (age) profiles, longitudinal performance of individuals and of groups can be established, and from there, the potential exists to employ machine learning methods to detect subtle changes in an individual’s cognitive processes over time. Correspondence to: Robert D McLeod, Department of Electrical & Computer Engineering, University of Manitoba, Winnipeg, Manitoba, R3T 5V6, Canada, Tel: 204-474-7360; E-mail: Robert.Mcleod@UManitoba.ca

Serious games to assess mild cognitive impairment: ‘The game is the assessment’