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Broccoli, a salad vegetable, and turmeric, herbs are known to humankind from times immemorial [1,2]. There are several observations documented in the literature regarding the beneficial effects of the compounds present in these two food gradients [3-5]. Now it is the high time for translating ingredients from kitchen to clinic because of translational and nutrigenomics research. In that context, broccoli and turmeric are two ideal foodstuffs. There are phytochemicals and antioxidant compounds in these two herbs that have profound health benefit ranging from preventive to the curative phase of diseases [6-8]. Antioxidants are believed to be beneficial, but it can act both as friend or foe varying upon the microenvironment of the milieu interior in the scenario of the molecular pathogenesis of a disease [9,10]. Clinical Trials with antioxidants have yet not produced many encouraging results [11,12]. Instead, other than ascorbic acid (vitamin C) the antioxidants including Vitamin E are proved to increase mortality in all causes [13,14]. Therefore, use of antioxidants must consider seriously, and from the point of the molecular pathogenesis of the diseases, their use should be justified. It is found that oxidative stress is associated with most of the diseases [15]. The major noncommunicable chronic diseases of the recent times like diabetes mellitus, obesity, atherosclerosis etc. are related to oxidative stress [16]. In such conditions, supplementations of the antioxidant vitamins are not expected to improve the levels of the antioxidant enzymes [17]. It is particularly noteworthy that the activity of antioxidant enzymes is observed to be diminished in these chronic illnesses. In this context, there is a ray of hope from broccoli and curcumin.

The lesson to be learned from Broccoli and turmeric