English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background/aim: Acinetobacter baumannii is one of the most commonly encountered as multiresistance microorganism. This study was designated for investigating of β-lactamases resistance genes and aminoglycosides modifying enzymes (AMEs) in Acinetobacter baumannii isolated from Iraqi patients. Materials and methods: A total of 36 A. baumannii isolates were recovered from hospitalized Iraqi patients during May to September 2012. Antibiotic susceptibility test was performed against aminoglycosides antibiotics and phenotypic detection of slactamases was done using Extended Spectrum Beta Lacatmases (ESβL) strip. Polymerase Chain Reaction (PCR) amplification was achieved for investigating β-lactamases genes (blaSHV, blaTEM, and blaCTX) and aminoglycosides modifying enzymes (aac(6)Ib, ant(4')-IIb, aa(c) 3′ and aph(3′)-VI). Results: Out of 36 A. baumannii isolates, 15 (41.66%) were resistant to aminoglycosides antibiotics according to disk diffusion method. 17 (47.22%) isolates gave positive results in the preliminary screening of β-lactamases, the ESβLs type and AmpC enzyme, while 13 (36.11% ) of the isolates gave a positive result in Metallo-βlactamases production test. PCR analysis demonstrated that blaTEM was detected in 3 (20%) of the resistant isolates , blaSHV was detected in 9 (60%) , blaCTX-M was detected in 11 (73.33%), aac (6)-Ib was detected in 7 (46.66%), ant(4')-IIb was detected in 5(33.33%) , aph(3′)-VI in 2 (13.33%), and aa(c) 3′ was found in 10 (66.66%) of the resistant isolates. Conclusion: Local A. baumannii isolates with AMEs and β-lactamases genes represent a powerful nosocomial pathogen that threat the antibiotic era and life of immunocompromied and hospitalizes patients and this should be taken into account to find a new ways for the restriction of these powerful pathogens.

Detection of aminoglycoside modifying enzymes and β-lactamases in Acinetobacter baumannii isolated from hospitalized Iraqi patients