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Adhesion molecule (E-selectin, ICAM-1 and VCAM-1) have a crucial role in neutrophil extravasation caused by endothelial cell activation in viral Dengue infection. In overnutritious state, the serum adiponectin level is tend to be lower which limit its ability to inhibit the expression of pro inflammatory cytokines (TNFα, IL-6 and NF-kB) and adhesion molecules. There is also increased level of TNFα, IL-1 β, IL-6, IL-8 which increase the expression of adhesion molecules even further. However, the role of sE-selectin, sICAM-1 and sVCAM-1 in pediatric DHF patient with overweight is need to be evaluated. Methods: An analytic observational nested case-control study was conducted in Paediatric Division Sanglah General Hospital, Bali, Indonesia from January 2015 to October 2016 which DHF as a cases and DD as a control. Diagnosis of dengue infection was according to

bali medical journal

Dengue hemorrhagic fever: The role of Soluble E-Selektin, Soluble Intra Cellular Adhesion Molecule-1 (Sicam-1) and Soluble Vascular Cellular Adhesion Molecule -1 (Svcam-1) in overweight children